SPRB
Spruce Biosciences, Inc. Common Stock
stockNASDAQ
At CloseOct 15, 2026 3:59:50 PM EDT
41.65USD+6.862%(+2.67)63,772
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119.70M
Healthcare
Biotechnology
HQ
South San Francisco, CA, USA
Previous Close
$38.98
Beta
1.56
52-Week High
$179.95 2025-10-15
52-Week Low
$38.06 2026-10-14
SMA 50
$51.34
SMA 200
$58.02
Avg. Vol 10D
81,719
Avg. Vol 30D
102,505
Avg. Vol 90D
80,023
Relative Vol
0.56
2.87M
2.16M
75.33%
431,541
19.93%
4.53
71%/29%
73.41%
60.94%
2.1200%
400,000
95
770
1,467
Nov 9, 2026 (25d)
Aug 7, 2025 · 1-for-75 (reverse)
Oct 8, 2026
Oct 5, 2026
B.Riley reiterates Buy on Spruce Biosciences stock, $160 target · 
Investing.com
Sep 24, 2026
Sep 17, 2026
Spruce Biosciences at H.C. Wainwright: BLA path comes into focus · Investing.com
SPRB Profile
spruce biosciences is a clinical stage biopharmaceutical company focused on developing novel therapies for rare diseases affecting the endocrine system.
SPRB Performance
| Period | Price | Date | Change | Beta |
|---|---|---|---|---|
| 1W | 45.54 | 2026-10-08 | -8.54% | -0.115 |
| 1M | 55.17 | 2026-09-15 | -24.50% | 0.407 |
| 3M | 45.44 | 2026-07-15 | -8.34% | 1.228 |
| 6M | 69.32 | 2026-04-15 | -39.92% | 1.759 |
| 1Y | 159.06 | 2025-10-15 | -73.81% | 1.559 |
| 2Y | 0.47 | 2024-10-15 | +8814.81% | — |
| 5Y | 4.48 | 2021-10-15 | +829.69% | -0.057 |
SPRB Stock Summary
Spruce Biosciences, Inc. Common Stock (NASDAQ:SPRB) stock price today is $41.65, and today's volume is 57,664. SPRB is up 6.850% today. The 30 day average volume is 102,505. SPRB market cap is $119.70M with 2.87M shares outstanding.