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$RDGL biotech/FDA play. Applying for IDE to start human trials. Company committed to applying within the next 50ish days I think it is now. I'll share a quick write up I did on another post. Like any early stage biotech/FDA play, high risk high reward so becareful.
Vivos Inc (formally known as Radiogel)
RDGL - OTCQB
Biotech, kind of FDA play
They have a patented treatment process where they inject Y90 into a tumor using a hydrogel mix with a small gauge needle in a grid pattern. Basically the gel is more of a liquid and after it's injected, it warms up to the body temperature and becomes more a gel than a liquid.
Once it gets up to the body temperature, it holds the Y90 in place within the tumor. The Y90 gives off high doses of radiation, but the radiation only travels a short distance. Y90 is already a well studied isotope that is used in many medical uses so they know a lot about it. You can basically have your children on your lap even after being injected due to the short distance the radiation travels unlike other isotopes.
Due to the short distance of the radiation travel, they can inject it and basically only give high doses of radiation from within the tumor or any area they want to be effected. Their moto is basically "precision". With Y90 half life of roughly 2.5 days, after 10 days the tumor receives almost the entire dose of radiation. After about 3 months there's a natural body cycle that will remove the dead tumor and the hydrogel. At this point the Y90 is long gone.
The cool thing is that they've been treating animals with this for years. Matter of fact, we had a horse treated with it when it had a tumor on it's tail. It was a same day treatment where the animal can go home the same day. They started using it at state universities, but now have expanded into private clinics. This year they are focusing on expanding to more clinics. I think they are expecting to be in over 20 by the end of the year. They also are being used at Johns Hopkins at their animal hospital.
Their animal division is called Isopet. It will be a little while before Isopet becomes profitable as they start to expand and gain market share, but the real money will be in their human division, Radiogel. They are actively working with the FDA following all their requirements and requests to build a IDE submission (to start human trials) that will be bullet proof.
They even used a special program from the FDA called the Early Feasibility Study (EFS) to basically have the FDA walk you through every thing they want and have many meetings with them. Shortly after the EFS, the company was granted the Break Through Device Designation (BDD). The BDD is basically the FDA saying you meet the requirements of having a product or treatment that is safer, more effective, and likely to help people with life threatening issues.
The BDD also can speed up human trials if approved because they want to get the life saving treatment to market ASAP.
Another use for this is to kill dirty margin. Once a doctor cuts out cancer, it's hard to get all the cancer cells. They have used this to give radiation to the area of where the cancer was removed and has successfully reduced the chance of it coming back. The doctor doesn't want to cut out more than they have to.
Doctors from the Mayo Clinic actually approached the company about getting involved to get this to market as they saw massive potential in this for so many cancers and other non cancer treatments. The Mayo Clinic doesn't allow their doctors to work directly for for-profit companies, but the Mayo Clinic gave special permission to their doctors to work with this company and help consult them. Now the Mayo Clinic has officially agreed to perform the human trials once they receive the IDE from the FDA.
A top oncologist from India reached out to the company and asked them to bring this to his country. While they wait for the approval from the FDA, they are actively doing human trials in India as I type this. So far they have had massive success and are expanding the trail from their original indication of thyroid cancer in 5 people to 50 more patients with cancer anywhere in the body.
To sum this up, this company has made a cancer treatment that can treat cancer basically anywhere in the body, including sensitive areas such as the brain and spine or anywhere in the body. They are currently making more uses and products for different situations. The animal treatment is starting to gain traction. They are in the process of going international already.
This is a long term investment in my eyes, but if you have time, this could be one of those companies that everyone wishes they had got into for pennies and not $10+.
I want to be very clear, this is not a cure for cancer. It's just another tool in the doctor's toolbox. Hopefully a very effective one that will make a difference for many. It may help slow down the spreading of the cancer, but it's treatment is made for cancer that hasn't spread such as a solid tumor. I think they could use this to attack the tumors and use chemo for the spreading aspect.

$RDGL biotech/FDA play. Applying for IDE to start human trials. Company committed to applying within the next 50ish days I think it is now. I'll share a quick write up I did on another post. Like any early stage biotech/FDA play, high risk high reward so becareful.
Vivos Inc (formally known as Radiogel)
RDGL - OTCQB
Biotech, kind of FDA play
They have a patented treatment process where they inject Y90 into a tumor using a hydrogel mix with a small gauge needle in a grid pattern. Basically the gel is more of a liquid and after it's injected, it warms up to the body temperature and becomes more a gel than a liquid.
Once it gets up to the body temperature, it holds the Y90 in place within the tumor. The Y90 gives off high doses of radiation, but the radiation only travels a short distance. Y90 is already a well studied isotope that is used in many medical uses so they know a lot about it. You can basically have your children on your lap even after being injected due to the short distance the radiation travels unlike other isotopes.
Due to the short distance of the radiation travel, they can inject it and basically only give high doses of radiation from within the tumor or any area they want to be effected. Their moto is basically "precision". With Y90 half life of roughly 2.5 days, after 10 days the tumor receives almost the entire dose of radiation. After about 3 months there's a natural body cycle that will remove the dead tumor and the hydrogel. At this point the Y90 is long gone.
The cool thing is that they've been treating animals with this for years. Matter of fact, we had a horse treated with it when it had a tumor on it's tail. It was a same day treatment where the animal can go home the same day. They started using it at state universities, but now have expanded into private clinics. This year they are focusing on expanding to more clinics. I think they are expecting to be in over 20 by the end of the year. They also are being used at Johns Hopkins at their animal hospital.
Their animal division is called Isopet. It will be a little while before Isopet becomes profitable as they start to expand and gain market share, but the real money will be in their human division, Radiogel. They are actively working with the FDA following all their requirements and requests to build a IDE submission (to start human trials) that will be bullet proof.
They even used a special program from the FDA called the Early Feasibility Study (EFS) to basically have the FDA walk you through every thing they want and have many meetings with them. Shortly after the EFS, the company was granted the Break Through Device Designation (BDD). The BDD is basically the FDA saying you meet the requirements of having a product or treatment that is safer, more effective, and likely to help people with life threatening issues.
The BDD also can speed up human trials if approved because they want to get the life saving treatment to market ASAP.
Another use for this is to kill dirty margin. Once a doctor cuts out cancer, it's hard to get all the cancer cells. They have used this to give radiation to the area of where the cancer was removed and has successfully reduced the chance of it coming back. The doctor doesn't want to cut out more than they have to.
Doctors from the Mayo Clinic actually approached the company about getting involved to get this to market as they saw massive potential in this for so many cancers and other non cancer treatments. The Mayo Clinic doesn't allow their doctors to work directly for for-profit companies, but the Mayo Clinic gave special permission to their doctors to work with this company and help consult them. Now the Mayo Clinic has officially agreed to perform the human trials once they receive the IDE from the FDA.
A top oncologist from India reached out to the company and asked them to bring this to his country. While they wait for the approval from the FDA, they are actively doing human trials in India as I type this. So far they have had massive success and are expanding the trail from their original indication of thyroid cancer in 5 people to 50 more patients with cancer anywhere in the body.
To sum this up, this company has made a cancer treatment that can treat cancer basically anywhere in the body, including sensitive areas such as the brain and spine or anywhere in the body. They are currently making more uses and products for different situations. The animal treatment is starting to gain traction. They are in the process of going international already.
This is a long term investment in my eyes, but if you have time, this could be one of those companies that everyone wishes they had got into for pennies and not $10+.
I want to be very clear, this is not a cure for cancer. It's just another tool in the doctor's toolbox. Hopefully a very effective one that will make a difference for many. It may help slow down the spreading of the cancer, but it's treatment is made for cancer that hasn't spread such as a solid tumor. I think they could use this to attack the tumors and use chemo for the spreading aspect.