GlobeNewswire Inc | Nov 2, 2020 05:24PM EST

November 02, 2020

SYDNEY, Australia, Nov. 02, 2020 (GLOBE NEWSWIRE) -- Immutep Limited (ASX: IMM; NASDAQ: IMMP) (Immutep or the Company), a biotechnology company developing novel immunotherapy treatments for cancer and autoimmune diseases, is pleased to announce more mature interim data from its phase II TACTI-002 study of eftilagimod alpha (efti) has been accepted as a late breaker poster presentation and poster walk for highly scored abstracts at the Society for Immunotherapy of Cancer (SITC) 35th Anniversary 2020 Annual Meeting, which is taking place as a virtual event from 9-14 November, US Eastern Standard Time (US EST).

SITC is the worlds leading member society of medical professionals dedicated to advancing cancer immunotherapy and biological therapy. Its Annual Meeting is a multidisciplinary educational and interactive conference focused on improving cancer patient outcomes.

ImmutepsPoster Presentation:

A Phase II study (TACTI-002) of eftilagimod alpha (a soluble LAG-3Abstract t protein) with pembrolizumab in PD-L1 unselected patients withitle: metastatic non-small cell lung (NSCLC) or head and neck carcinoma ( HNSCC)Abstract # 790:Date & Monday 9 November 2020, 8am US ESTtime:Presenter: Dr Matthew Krebs, The Christie NHS Foundation Trust, Manchester, UK

Immutep will make the poster presentation available on its website following its publication at SITC 2020.

About TACTI-002TACTI-002 is being conducted in collaboration with Merck & Co., Inc., Kenilworth, NJ, USA (known as MSD outside the United States and Canada). It is evaluating the combination of efti with MSDs KEYTRUDA (or pembrolizumab, an anti-PD-1 therapy) in up to 109 patients.

About ImmutepImmutep is a globally active biotechnology company that is a leader in the development of LAG-3 immunotherapies for the treatment of cancer and autoimmune disease. Immutep is dedicated to leveraging its technology and expertise to bring innovative treatment options to market for patients and to maximize value to shareholders. Immutep is listed on the Australian Securities Exchange (IMM) and the NASDAQ (IMMP) in the United States.

Immuteps current lead product candidate is eftilagimod alpha (efti or IMP321), a soluble LAG-3Ig fusion protein which is a first-in-class antigen presenting cell (APC) activator and is being explored in cancer and infectious disease.

Additional LAG-3 products, including antibodies, for immune response modulation in autoimmunity and cancer are being developed by Immuteps large pharmaceutical partners. Immutep is also developing an agonist of LAG-3 (IMP761) for autoimmune disease.

Further information can be found on the Companys website www.immutep.com or by contacting:

Australian Investors/Media:Catherine Strong, Citadel-MAGNUS+61 (0)406 759 268; cstrong@citadelmagnus.com

U.S. Media:Tim McCarthy, LifeSci Advisors+1 (212) 915.2564;tim@lifesciadvisors.com

This announcement was authorised for release by the Chief Executive Officer of Immutep Limited.