GlobeNewswire Inc | Jan 5, 2021 06:30AM EST

January 05, 2021

CAMBRIDGE, Mass., Jan. 05, 2021 (GLOBE NEWSWIRE) -- Generation Bio Co. (Nasdaq: GBIO), an innovative genetic medicines company creating a new class of non-viral gene therapy, announced today that the company will present at the virtual 39th Annual J.P. Morgan Healthcare Conference on Tuesday, Jan. 12, 2021.

President and Chief Executive Officer Geoff McDonough, M.D., will provide an overview of the companys progress and anticipated milestones for 2021.

Generation Bio this week announced a scientific milestone with the first demonstration of a non-viral gene therapy platform enabling human factor VIII expression in mice with hemophilia A. Mean levels of factor VIII reached 23% of normal levels.

The company also announced data confirming successful translation of the companys liver-targeted lipid nanoparticle delivery system into non-human primates. Together, the data support the advancement of Generation Bios lead program in hemophilia A into IND-enabling studies.

Presentation DetailsDate: Tuesday, Jan. 12, 2021Time: 2:50-3:30 p.m. ET

A live webcast of the company presentation and Q&A session will be available on the investor section of the companys website at investors.generationbio.com. A replay will be available there for 30 days following the event.

About Generation Bio

Generation Biois an innovative genetic medicines company focused on creating a new class of non-viral gene therapy to provide durable, redosable treatments for people living with rare and prevalent diseases. The companys non-viral platform incorporates a proprietary, high-capacity DNA construct called closed-ended DNA, or ceDNA; a cell-targeted lipid nanoparticle delivery system, or ctLNP; and an established, scalable capsid-free manufacturing process. The platform is designed to enable multi-year durability from a single dose of ceDNA and to allow titration and redosing if needed. The ctLNP is designed to deliver large genetic payloads, including multiple genes, to specific tissues to address a wide range of indications. The companys efficient, scalable manufacturing process supports Generation Bios mission to extend the reach of gene therapy to more people, living with more diseases, in more places around the world.

For more information, please visitwww.generationbio.com.

Contact:

InvestorsMaren KillackeyGeneration Biomkillackey@generationbio.com541-646-2420

MediaAlicia WebbGeneration Bioawebb@generationbio.com847-254-4275

Stephanie SimonTenBridge Communicationsstephanie@tenbridgecommunications.com617-581-9333