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Immix Biopharma's IMX-110 / Anti-PD-1 Combo Therapy Shows Extended Median Survival In Animal Studies


Benzinga | Jan 25, 2022 12:17PM EST

Immix Biopharma's IMX-110 / Anti-PD-1 Combo Therapy Shows Extended Median Survival In Animal Studies

Immix Biopharma Inc's (NASDAQ:IMMX) IMX-110 + anti-PD-1 produced 63-day median survival in a genetic pancreatic cancer mouse model, in which mice develop their own pancreatic cancer and have an intact immune system.

* Historically, 42-days is the median survival produced by a 4-drug combination: 2 chemotherapies and two immunotherapies in the same genetic pancreatic cancer mouse model.

* "This data highlights why we are excited to collaborate with BeiGene on our planned 2022 Phase 1b/2a combination trial of IMX-110 + BeiGene anti-PD-1 tislelizumab in advanced solid tumors," said Ilya Rachman, CEO of ImmixBio. "We believe this upcoming combination clinical trial will allow us to expand into multiple oncology indications rapidly."

* In 2022, the Company plans to commence combination IMX-110 + BeiGene Ltd (NASDAQ:BGNE) anti-PD-1 tislelizumab Phase 1b/2a clinical trial in advanced solid tumors.

* Related: Immix's Lead Program Shows 50% Response Rate In Resistant Cancer In Animal Study.

* The FDA has approved orphan drug designation for IMX-110 for soft tissue sarcoma. Additionally, the FDA has approved rare pediatric disease designation to IMX-110 for rhabdomyosarcoma.

* Price Action: IMMX shares are down 3.07% at $4.10 during the market session on the last check Tuesday.







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