Benzinga | Nov 22, 2021 11:15AM EST

RegenXbio's Duchenne Gene Therapy Secures FDA Orphan Drug Tag

The FDA has granted Orphan Drug Designation to RegenXbio Inc's (NASDAQ:RGNX) RGX-202, potential one-time gene therapy for Duchenne muscular dystrophy (Duchenne).

* Duchenne is a genetic disorder characterized by progressive muscle degeneration and weakness due to the alterations of a protein called dystrophin that helps keep muscle cells intact.

* RGX-202 is designed to deliver optimized microdystrophin transgene with a unique C-terminal domain and a muscle-specific promoter to support targeted therapy for improved resistance to muscle damage associated with Duchenne.

* RGX-202 uses RegenXbio's proprietary NAV AAV8 vector.

* The Company expects to submit an Investigational New Drug (IND) application to the FDA for RGX-202 by the end of 2021.

* Related content: Benzinga's Full FDA Calendar.

* Price Action: RGNX shares are up 0.66% at $33.73 during the market session on the last check Monday.