Benzinga | Nov 19, 2021 07:15AM EST

Safety Signals Force Enanta To Stop EDP-721 HBV Program

* Enanta Pharmaceuticals Inc (NASDAQ:ENTA) has decided to discontinue the development of EDP-721, an oral Hepatitis B Virus (HBV) RNA destabilizer.

* The move follows safety signals observed in the single ascending dose part of a Phase 1 study in healthy volunteers.

* "Despite the clean preclinical safety profile demonstrated in comprehensive toxicology studies, safety signals were seen in healthy subjects after administration of EDP-721.

* The Company will continue to focus on developing EDP-514 in combination regimens as a functional cure for HBV.

* Related: Enanta To Discontinue Internal Development Of NASH Candidates.

* Price Action: ENTA shares closed at $92.58 on Thursday.