Benzinga | Nov 2, 2021 11:24AM EDT

Equillium Reveals Early Safety Data For Itolizumab In Lupus Patients

* Equillium Inc (NASDAQ:EQ) announced interim data from the Type A portion of the Phase 1b EQUALISE study in systemic lupus erythematosus (SLE) patients.

* Data were presented at the American College of Rheumatology (ACR) annual meeting.

* The data showed that itolizumab administration was well tolerated and decreased proteinuria and albuminuria, two key biomarkers of disease risk.

* The data showed that for SLE patients with baseline urine protein-to-creatinine ratios (UPCR) over 100 mg/g (N=16) and 200 mg/g (N=6), UPCR 34% and 42% declined, respectively, at Day 57.

* In addition, for patients with baseline urine albumin-to-creatinine ratio (UACR) of more than 30 mg/g (N=4), there was a decline of 54% at Day 57.

* The Type B portion of the EQUALISE study will evaluate up to 20 newly diagnosed or refractory lupus nephritis patients who will be treated with itolizumab dosed at 1.6 mg/kg SC Q2W for up to 24 weeks.

* Related Link: Equillium's Itolizumab Reduces Urine Protein In Lupus Patients.

* Price Action: EQ shares are up 0.80% at $6.28 during the market session on the last check Tuesday.