GlobeNewswire Inc | Nov 20, 2020 08:40AM EST

November 20, 2020

Prof. June is a world authority on immune tolerance and adoptive immunotherapy

Appointmentreaffirms AC Immunes scientificleadership in neurodegeneration

LAUSANNE, Switzerland, Nov. 20, 2020 (GLOBE NEWSWIRE) -- AC Immune SA (NASDAQ: ACIU), a Swiss-based, clinical-stage biopharmaceutical company with a broad pipeline focused on neurodegenerative diseases, today announced that Prof. Carl H. June, a world authority on mechanisms related to immune tolerance and adoptive immunotherapy in the fields of chronic inflammation and cancer, was elected to the Companys Board of Directors, at an extraordinary shareholders meeting today.

Prof. June is a true pioneer in the field of immunotherapy most well-known for his research into T cell therapies for the treatment of cancer, who, in 2020, was elected to the American Philosophical Society. His expertise can further accelerate AC Immunes progress in advancing its pipeline of immunotherapies and therapies targeting neuroinflammation.

Prof. Andrea Pfeifer, CEO of AC Immune SA, commented We welcome Prof. Junes timely appointment, as neurodegeneration is increasingly linked to inflammatory mechanisms, a key scientific focus for AC Immunes discovery efforts. His appointment is a further affirmation of our scientific leadership in the neurodegenerative disease field. Prof. Junes significant expertise and standing in the scientific community will be an invaluable asset as we work to develop innovative immunotherapies and target neuroinflammation using our proprietary technology platforms.

Prof. June commented I am proud to be invited to join the Board of Directors of AC Immune, an established pioneer at the forefront of discovering and developing treatments for neurodegenerative diseases. It is tremendously exciting to be involved at the cutting edge of research addressing an area with such a high unmet medical need, where immunotherapy and inflammation could play a critically important role. I look forward to working with the outstanding team at AC Immune and hope my own expertise will contribute to their continued success.

Prof. June is Richard W. Vague Professor in Immunotherapy, Director of the Center for Cellular Immunotherapies and Director of the Parker Institute for Cancer Immunotherapy at the Perelman School of Medicine at the University of Pennsylvania. Due to his lifelong work on lymphocyte activation, Prof. June is considered a world authority on mechanisms related to immune tolerance and adoptive immunotherapy in the fields of chronic inflammation and cancer. He and his team pioneered the groundbreaking work in immunotherapy in which patients with refractory and relapsed chronic lymphocytic leukemia are treated with genetically engineered versions of their own T cells. This CAR-T therapy approach, which trains the immune system to attack and destroy cancer cells, has opened a new era of innovative treatments and personalized medicine for cancer patients.

Prof. June is a graduate of the Naval Academy in Annapolis, USA, and Baylor College of Medicine in Houston, USA, where he received his medical degree. Prof. June also completed graduate training in immunology and malaria with Dr. Paul-Henri Lambert at the World Health Organization, Geneva, Switzerland, and post-doctoral training in transplantation biology with E. Donnell Thomas and John Hansen at the Fred Hutchinson Cancer Research Center in Seattle, USA. He has published more than 500 manuscripts and is the recipient of numerous honors and prizes.

About AC Immune SA AC Immune SAis a Nasdaq-listed clinical-stage biopharmaceutical company, which aims to become a global leader in precision medicine for neurodegenerative diseases. The Company utilizes two proprietary platforms, SupraAntigenand Morphomer, to design, discover and develop small molecule and biological therapeutics as well as diagnostic products intended to diagnose, prevent, and modify neurodegenerative diseases caused by misfolding proteins. The Company's pipeline features nine therapeutic and three diagnostic product candidates, with six currently in clinical trials. It has collaborations with major pharmaceutical companies includingGenentech, a member of the Roche Group, Eli Lilly and Company andJanssen Pharmaceuticals.

For further information, please contact:

Head of Investor Relations US MediaJoshua Drumm, Ph.D. Katie GallagherAC Immune LaVoie HealthSciencePhone: +1 917 809 0814 Phone: +1 617 792 3937Email: joshua.drumm@acimmune.com Email: kgallagher@lavoiehealthscience.com Global Head of Communications European Investors & MediaJudith Moore Chris MaggosAC Immune LifeSci AdvisorsPhone: +41 79 826 63 82 Phone: +41 79 367 6254Email: judith.moore@acimmune.com Email: chris@lifesciadvisors.com

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