Benzinga | Oct 4, 2021 07:37AM EDT

MediWound Announces Peer-Reviewed Publication Of EscharEx In-Vivo Head-To-Head Comparator Study In The Journal Of Wound Care

MediWound Ltd. (NASDAQ:MDWD), a fully-integrated biopharmaceutical company focused on next-generation bio-therapeutic solutions for tissue repair and regeneration, today announced a peer-reviewed publication in the Journal of Wound Care of an in vivo head-to-head study comparing EscharEx(r) and a commercial enzymatic debridement agent in the removal of chronic wound eschar. The study concluded that EscharEx was more effective than the commercially available collagenase in removing the eschar in this wound model.

The paper, entitled Development of a porcine chronic wound model: Evaluation of a bromelain-based enzymatic debriding agent1, describes the development of a novel porcine eschar model and compares the debridement efficacy of various concentrations of EscharEx, a novel bromelain-based enzymatic debridement agent, with commercially available collagenase-based debridement agent. Study results demonstrated that EscharEx treatment was more effective than the commercially available collagenase agent in debriding eschars in this novel porcine wound model.

"We are excited to have the study results published in this esteemed journal. The data clearly demonstrate EscharEx was superior to the commercially available enzymatic debriding agent in removing eschar," said Sharon Malka, Chief Executive Officer of MediWound. "The data generated to date, together with the successful interim assessment of our ongoing U.S. phase 2 study to treat patients with venous leg ulcers, give us confidence in our clinical development plan, and we look forward to report data from our phase 2 study in the first half of next year. EscharEx may offer significant benefits for patients and healthcare professionals in the care of chronic wounds, addressing a clear medical need for a rapid and effective non-surgical debridement agent, and we believe it has the potential to change the standard of care in this sizeable market."