GlobeNewswire Inc | Sep 27, 2021 07:00AM EDT

September 27, 2021

Benzinga Healthcare Small Cap Conference on September 29-30, 2021

Ophthalmology Futures Forums: European Virtual Forum on October 7, 2021

Alliance Global Partners Biotech & Specialty Pharma Conference on October 13, 2021

FARMINGTON HILLS, Mich., Sept. 27, 2021 (GLOBE NEWSWIRE) -- Ocuphire Pharma, Inc. (Nasdaq: OCUP), a clinical-stage ophthalmic biopharmaceutical company focused on developing and commercializing therapies for the treatment of refractive and retinal eye disorders, today announced that Mina Sooch, President and Chief Executive Officer will be presenting corporate overviews at the Benzinga Healthcare Small Cap Conference on Wednesday, September 29th and the Ophthalmology Futures Forums: 2021 European Virtual Forum Key Topics on Thursday, October 7th as well as participating in the Treatment Age Related Diseases Panel at Alliance Global Partners (A.G.P.) Biotech & Specialty Pharma Conference on Wednesday, October 13th.

Benzinga Healthcare Small Cap Conference ? September 29-30, 2021 Title: Ocuphire Pharma (OCUP) Company PresentationDate: Wednesday, September 29, 2021Time: 9:50 AM EDT and 1X1 MeetingsPresenter: Mina Sooch, CEOConference LinkRegis.: Ophthalmology Futures Forums: 2021 European Virtual Forum ? October 7, 2021 Title: Ocuphire Pharma (OCUP) Company PresentationDate: Thursday, October 7, 2021Time: Company Presentations Track (European Time)Presenter: Mina Sooch, CEOConference LinkRegis.: Alliance Global Partners Biotech & Specialty Pharma Conference ? October 13,2021

Title Panel: Treating Age Related Diseases: Aging Eyes, Diabetes, and Inflammatory DiseasesDate: Wednesday, October 13, 2021Time: 3:00 PM EDT and 1X1 MeetingsPresenter: Mina Sooch, CEO Ocuphire Pharma (OCUP)Conference Contact AGP representativeRegis.:

If you are interested in arranging a 1X1 meeting request, please contact your bank/conference representative orir@ocuphire.com. For more details, please see theInvestorsandEventssection of Ocuphires corporate website.

About Ocuphire Pharma

Ocuphire is a publicly traded (NASDAQ: OCUP), clinical-stage ophthalmic biopharmaceutical company focused on developing and commercializing therapies for the treatment of several eye disorders. Ocuphires pipeline currently includes two small-molecule product candidates targeting front and back of the eye indications. The companys lead product candidate, Nyxol(0.75% phentolamine ophthalmic solution) Eye Drops, is a once-daily preservative-free eye drop formulation of phentolamine mesylate, a non-selective alpha-1 and alpha-2 adrenergic antagonist designed to reduce pupil size, and is being developed for several indications, including dim light or night vision disturbances (NVD), reversal of pharmacologically-induced mydriasis (RM), and presbyopia, and has been studied in 9 clinical trials including the recently completed Phase 3 trial in RM and Phase 2 trial in presbyopia. Ocuphire reported positive topline data in March 2021 for MIRA-2, a Phase 3 FDA registration study for treatment of RM. Ocuphire also reported positive top-line data in June 2021 for VEGA-1, a Phase 2 trial for the treatment of presbyopia. Nyxol is also currently in Phase 3 clinical development for NVD. Ocuphires second product candidate, APX3330, is an oral tablet designed to inhibit angiogenesis and inflammation pathways relevant to retinal and choroidal vascular diseases; such as diabetic retinopathy (DR) and diabetic macular edema (DME) and has been studied in 11 Phase 1 and 2 trials. APX3330is currently enrolling subjects ina Phase 2 clinical trial in subjects with DR/DME. As part of its strategy, Ocuphire will continue to explore opportunities to acquire additional ophthalmic assets and to seek strategic partners for late-stage development, regulatory preparation, and commercialization of drugs in key global markets. Please visitwww.clinicaltrials.govto learn more about Ocuphires completed Phase 2 trials, recently completed Phase 3 registration trial in RM(NCT04620213), recently completed Phase 2 trial in presbyopia (NCT04675151), ongoing Phase 3 registration trial in NVD(NCT04638660), and Phase 2 trial in DR/DME (NCT04692688). For more information, please visitwww.ocuphire.com.

Forward Looking Statements

Statements contained in this press release regarding matters that are not historical facts are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based upon Ocuphires current expectations and involve assumptions that may never materialize or may prove to be incorrect. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, including, without limitation: (i) the success and timing of regulatory submissions and pre-clinical and clinical trials, including enrollment and data readouts; (ii) regulatory requirements or developments; (iii) changes to clinical trial designs and regulatory pathways; (iv) changes in capital resource requirements; (v) risks related to the inability of Ocuphire to obtain sufficient additional capital to continue to advance its product candidates and its preclinical programs; (vi) legislative, regulatory, political and economic developments, (vii) changes in market opportunities, (viii) the effects of COVID-19 on clinical programs and business operations, (ix) the success and timing of commercialization of any of Ocuphires product candidates and (x) the maintenance of Ocuphires intellectual property rights. The foregoing review of important factors that could cause actual events to differ from expectations should not be construed as exhaustive and should be read in conjunction with statements that are included herein and elsewhere, including the risk factors detailed in documents that have been and may be filed by Ocuphire from time to time with the SEC. All forward-looking statements contained in this press release speak only as of the date on which they were made. Ocuphire undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

Ocuphire Contacts

Mina Sooch, President & CEOOcuphire Pharma, Inc.ir@ocuphire.comwww.ocuphire.com

Corey Davis, Ph.D.LifeSci Advisorscdavis@lifesciadvisors.com