Benzinga | Jul 22, 2021 09:28AM EDT

Adagene To Test Its Anti-CTLA-4 Monoclonal Antibodies In Combination With Keytruda In Solid Tumors

* Adagene Inc (NASDAQ:ADAG) has entered into a clinical trial collaboration and supply agreement with Merck & Co Inc (NYSE:MRK).

* The agreement includes two clinical studies to evaluate Adagene's anti-CTLA-4 monoclonal antibody (mAb) candidates, ADG116 and ADG126, in combination with Merck's Keytruda (pembrolizumab), for patients with advanced/metastatic solid tumors.

* "ADG116 program is at the 3 mg/kg dose level now, which is where the commercial CTLA-4 therapy had been approved previously in mono and combination for specific indications," said Steven Fischkoff, interim Chief Medical Officer of Adagene.

* Price Action: ADAG shares are up 3.97% at $20.67 during the premarket session on the last check Thursday.