Benzinga | Jun 4, 2021 09:18AM EDT

AIkido Pharma Highlights Presentation Of Phase 1 Data At American Society Of Clinical Oncology Jun. 4

AIkido Pharma Inc. (NASDAQ:AIKI) ("AIkido" or the "Company") today announced that positive Phase 1 testing data was presented at the 2021 ASCO Annual Meeting June 4, 2021. The poster presentation of the data was by Dr. Scott Tagawa, a Professor of Medicine & Urology at Weill Cornell Medicine and an AIkido Pharma Scientific Advisory Board member. The full presentation is available at: https://conferences.asco.org



Highlights from the presentation include:

* Declining PSA levels in treated patients

* Declining circulating tumor cell (CTC) count in treated patients

* Actinium-225 radiolabeled J591 well-tolerated with preliminary evidence of efficacy in a heavily pre-treated patient population

* Actinium-225 radiolabeled J591 safe at tested dosage

* Phase 2 trial underway

Neal Shore, MD, FACS a well-known key opinion leader in prostate cancer research, Medical Director for the Carolina Urologic Research Center and recent addition to the Company's Advisory Board, stated, "The Phase I trial results of the 225Ac-J591 antibody for these advanced prostate cancer patients, who had extensive tumor burden as well as having experienced numerous life prolonging therapies, are impressive, both from a response and safety standpoint. PSA declines and CTC responses were clearly evident. Additionally, this novel antibody conjugate demonstrated very good tolerability during this DLT phase 1 trial. The unique properties of 225Ac-J591 suggest it as a very promising candidate for combination treatment with beta emitters, whereby the synergy of therapeutic isotope combination and broader tumor effect would have the potential to further shape theragnostic platforms."

Full ASCO Presentation Details:

Title: "Phase I study of 225Ac-J591 for men with metastatic castration-resistant prostate cancer (mCRPC)"

Tract: Genitourinary Cancer--Prostate, Testicular, and Penile

Presenter: Dr. Scott Tagawa MD, MS, FACP

Abstract Number: 5015

Date and Time: Available Starting June 4, 2021, 9:00 am (EST)

The Abstract from this study has been released on the ASCO Annual Meeting website ( https://conferences.asco.org). Clinical trial information: NCT03276572 ( https://meetinglibrary.asco.org/record/196409/abstract )

The full ASCO meeting program is available at: www.asco.org