Benzinga | May 17, 2021 08:14AM EDT

Zynerba Pharmaceuticals Announces Podium And Poster Presentations At International Society For Pharmacoeconomic And Outcomes Research (ISPOR) Virtual 2021 Conference

Zynerba Pharmaceuticals, Inc. (NASDAQ:ZYNE), the leader in innovative pharmaceutically-produced transdermal cannabinoid therapies for rare and near-rare neuropsychiatric disorders, today announced an oral podium presentation and a poster presentation at the Virtual ISPOR 2021 conference taking place May 17-20, 2021. Both the podium and poster presentations are available on the Virtual ISPOR 2021 program gallery and on the Zynerba corporate website at https://zynerba.com/publications/. ISPOR is the leading professional society for health economics and outcomes research (HEOR) globally.



The oral podium presentation, titled, "Caregiver-Perceived Behavioral Challenges in Fragile X Syndrome (FXS) and their Measurement using the Aberrant Behavior Checklist-Community FXS Specific Scoring" demonstrates that the ABC-CFXS subscales utilized to measure the primary and key secondary endpoints in Zynerba's CONNECT-FX trial capture behavioral challenges of relevance to patients with FXS and their families.

The poster, titled, "Meaningful Change Thresholds for the Aberrant Behavior Checklist-Community Fragile X Syndrome (ABC-CFXS) in Children and Adolescents With FXS," describes responder thresholds representing individual patient-level changes that may be indicative of meaningful treatment benefit for the ABC-CFXS social avoidance, irritability, and socially unresponsive/lethargic subscales. As such, these thresholds serve as a basis for evaluating clinically meaningful treatment effects at the individual patient level in clinical trials of children and adolescents with FXS as demonstrated in CONNECTFX.

"We believe these data demonstrate the ABC-CFXS subscales capture behaviors that are impactful and understandable to caregivers of children with FXS," said Joseph M. Palumbo, M.D., LFAPA, MACPsych, Chief Medical Officer of Zynerba. "Therefore, we remain confident that these subscales are fit for purpose for measuring clinical trial endpoints in FXS."