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Incyte Announces New Ruxolitinib Data From Atopic Dermatitis and Vitiligo Studies


Benzinga | Apr 23, 2021 01:20PM EDT

Incyte Announces New Ruxolitinib Data From Atopic Dermatitis and Vitiligo Studies

* Incyte Corporation (NASDAQ: INCY) has announced findings from three pooled analyses of its Phase 3 studies, TRuE-AD1 and TRuE-AD2 evaluating ruxolitinib cream to treat atopic dermatitis (AD).

* Data presented at the American Academy of Dermatology Virtual Meeting Experience 2021 showed Ruxolitinib demonstrated greater improvement in all analyzed efficacy endpoints than vehicle.

* A subsequent analysis of a subset of patients found higher clinical responses with ruxolitinib cream versus vehicle.

* At Week 8, more patients achieved treatment success with ruxolitinib cream 0.75% and ruxolitinib cream 1.5% versus vehicle (50.0% and 59.4% versus 0%, respectively).

* Patients who applied ruxolitinib cream 0.75% and ruxolitinib cream 1.5% versus vehicle achieved improvement in eczema severity at Week 8.

* At Week 8, more patients achieved improvement in itch with ruxolitinib cream 0.75% and ruxolitinib cream 1.5% versus vehicle (50.0% and 61.1% versus 27.3%).

* Incyte also announced updated data at Week 104 from the Phase 2 study with ruxolitinib cream in adult patients with vitiligo.

* New data showed continuous improvements in facial and total body repigmentation.

* Separately, an exploratory analysis evaluated the maintenance of repigmentation among patients. 75% of patients maintained total body repigmentation, and 81.3 % of patients held facial repigmentation during a follow-up duration of one to six months.

* Price Action: INCY shares are up 0.8% at $84.88 on the last check Friday.







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