Benzinga | Apr 5, 2021 11:46AM EDT

Can-Fite Says Cannabinoid-Based Therapies Stop Liver Cancer Growth, Preclinical Studies Show

* Can-Fite BioPharma (NYSE: CANF) has completed pre-clinical studies demonstrating that a Cannabidiol (CBD)-rich T3/C15 cannabis fraction induces inhibition of liver cancer cell growth.

* The company's lead drug candidate Namodenoson is expected to enter the Phase 3 study in Q4 2021.

* The studies showed that CBD-rich T3/C15 cannabis fraction inhibited the growth of liver HEP-3b hepatocellular carcinoma cells via the A3AR by inhibiting Wnt- and NF-kappa B-related regulatory pathways.

* The Wnt signaling pathway is known to be highly active in controlling the growth of liver cancer cells.

* The company has filed patent applications for cannabinoid-based therapies where the A3AR target is overexpressed, including liver cancer.

* Price Action: CANF shares are down 1.7% at $2.41 in the market session on the last check Monday.