Benzinga | Mar 30, 2021 05:24AM EDT

Aptinyx Awarded U.S. Patent 10,961,189 'Spiro-lactam NMDA receptor modulators and uses thereof'

Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotropin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions and pharmaceutical formulations comprising the polypeptides and polynucleotides of the disclosure and methods of using and producing same are also disclosed.

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