Benzinga | Mar 30, 2021 05:19AM EDT

OPKO Biologics Awarded U.S. Patent 10,960,058 'Long-acting coagulation factors and methods of producing same'

Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotropin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions and pharmaceutical formulations comprising the polypeptides and polynucleotides of the disclosure and methods of using and producing same are also disclosed.

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