Benzinga | Sep 25, 2020 07:11AM EDT

uniQure Announces Data Safety Monitoring Board Review Of Phase I/II Clinical Trial Of AMT-130 Says 'No significant safety concerns were noted to prevent further dosing, and the next two patients are now cleared for enrollment in the study'

LEXINGTON, Mass. and AMSTERDAM, Sept. 25, 2020 (GLOBE NEWSWIRE) -- uniQure N.V. (NASDAQ:QURE), a leading gene therapy company advancing transformative therapies for patients with severe medical needs, today announced that the independent Data Safety Monitoring Board (DSMB) overseeing the Phase I/II clinical trial of AMT-130 for the treatment of Huntington's disease has met and reviewed 90-day safety data from the first two patients enrolled in the trial. No significant safety concerns were noted to prevent further dosing, and the next two patients are now cleared for enrollment in the study. The Phase I/II study is a double-blind, randomized clinical trial being conducted in the United States. One patient has been treated with AMT-130, and one patient received the imitation surgery.



"We are very pleased with the positive outcome from this first DSMB meeting," said Ricardo Dolmetsch, president of research and development at uniQure. "We will now advance the study and expect to enroll the next two patients as soon as possible."