RTTNews | Sep 23, 2020 09:27AM EDT

09:27 Wednesday, September 23, 2020 (RTTNews.com) - MediciNova Inc.'s (MNOV) intranasal BC-PIV SARS-CoV-2 vaccine has successfully induced systemic serum IgG and mucosal IgA neutralizing antibodies against the S1 antigen (Ag) of SARS-CoV-2 in mice.

The SI protein of the virus is one of the key targets of COVID-19 vaccines. S1 contains a receptor-binding domain, allowing the virus to dock to body receptors, paving way for entry into cells and leading to infection.

The BC-PIV SARS-CoV-2 vaccine contains BC-PIV, an innovative non-transmissible viral vector derived from the recombinant human parainfluenza virus type 2 (hPIV2), and is co-developed by BioComo and Mie University. MediciNova has an agreement with BioComo and Mie University for joint development of the BC-PIV SARS-CoV-2 vaccine.

Read the original article on RTTNews ( https://www.rttnews.com/3130906/medicinova-covid-19-vaccine-induces-systemic-serum-igg-mucosal-iga-neutralizing-antibodies-in-mice.aspx)

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